Airports are the second-most-driven location in any GTA after the protagonist's home. Vice City's airport has appeared in aerial frames in Trailer 2 - briefly, but visibly.
For the broader system, see the airport system page.
What the aerial frames show
A multi-runway airport on the mainland, north-west of Vice City proper. Large terminal facade. Aprons with parked aircraft. Adjacent service infrastructure - hangars, fuel.
The real Miami International is in roughly the same relative position to downtown Miami. The visual layout in trailer aerials is consistent with that arrangement.
What it's likely to be used for
Aircraft acquisition - GTA's airports have always been the easiest way to find a plane to steal. Story missions involving cargo, smuggling or escape. Possibly a starting hangar for a property system, GTA Online-style.
Heist-side: airports historically host heists in GTA. The Vice City airport will probably feature in at least one mission.